Is Berberine Better Than Metformin in Treating Diabetes?

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No doubt…

Diabetes is classified as a real global epidemic…

Creating a fertile ground for related complications to take hold…

Like heart disease, kidney disease, retinopathy, peripheral neuropathy, and amputations, among others.

Many experts believe this fast-growing tidal wave of diabetes is the result of the growing global consumption of sugar and starch-based processed foods that are heavily and incessantly marketed to the masses.

But is this trend stoppable? Can diabetes be reversed?

And yes…

Type 2 diabetes is particularly reversible following dietary and lifestyle changes that dramatically reduce or eliminate sugar and starches!

Relying on medication or insulin to lower blood sugar will not improve your health and neither will it…

Counteract the debilitating effects of diabetes.

And it gets worse because…

It doesn’t reduce your risk of death from any of the related health complications of diabetes, including…

Stroke, heart attack, viral infection, and kidney disease.

Diabetes drugs have been associated with many negative side effects–some downright deadly.

In one large study called the ACCORD, that was published in the New England Journal of Medicine in 2008, the 10,000 patients who were being treated with insulin or blood sugar-lowering drugs were monitored and evaluated for their risk of heart attack, strokes and death.

The National Institute of Health ended the study prematurely because the medical intervention was leading to more heart attacks, strokes and deaths.

Many of the conventional medical interventions for lowering blood sugar actually increase insulin levels, which in turn cause more overall harm than good.

Avandia, one of the world’s best-selling diabetes drugs, has over 50,000 lawsuits filed in the U.S. alone…

Because the manufacturer failed to warn patients of the potential life-threatening side-effects that include stroke, heart failure, heart attack, bone fractures, vision loss, and ultimately, death.

While many of these drugs do lower blood glucose levels, there seems to be no hardcore proof that any of the drugs do actually reduce the risk of diabetes complications.

In fact, many of the conventional treatments have been found to exacerbate the complications of diabetes.

Below is a list of the most commonly used diabetes meds and their established primary side-effects:

  • Metformin: Increases insulin sensitivity. Side-effects include nausea, diarrhea, weight gain and Vitamin B12 depletion, which further increases the chances of neuropathy.
  • Sulfonylureas: It helps your body secrete more insulin. Side-effects include low blood sugar and weight gain.
  • Meglitinides: These drugs stimulate the pancreas to secrete more insulin. Side-effects include low blood sugar and weight gain.
  • Thiazolidinediones: Like Metformin, these meds make the body’s tissues more sensitive to insulin. Side-effects include weight gain and increased risk of heart failure and fractures. Avandia and Actos are examples of such drugs.
  • SGLT2 inhibitors: They prevent the kidneys from reabsorbing sugar into the blood. Instead, the sugar is excreted via the urine. Side-effects may include yeast infections, urinary tract infections, increased urination and hypotension (low blood pressure).
  • Insulin Therapy: Lowers blood glucose, but it’s a fat-storing hormone. As such, it causes weight gain, and if used in excess, can promote inflammation and hormonal imbalance.

Insulin treatment is also known to increase susceptibility to cancer.

Keep in mind that, while most of these diabetes medications may lower blood sugar levels, stimulate insulin production, or make the body cells more insulin-sensitive…

They still do not prevent the serious and life-threatening complications of diabetes–high blood pressure, high LDL cholesterol, high triglycerides, low sex drive, infertility, blood clots, kidney failure, infections, amputations, blindness, cancer, depression, heart disease, strokes, Alzheimer’s, and much more.

The connection between diabetes and cancer is fairly clear…

Several studies have shown up to a 30% greater likelihood that diabetic patients on supplemental insulin can develop colon, breast, or prostate cancers.

Turning to berberine…

It’s been found to be especially effective for treating type 2 diabetes.

Berberine is a powerful plant extract with several impressive health benefits. It can effectively lower blood sugar, help reduce weight and improve heart health…

Two things most pharmaceutical diabetes drugs cannot do.

It’s also an anti-inflammatory and antimicrobial, besides being effective against diarrhea, intestinal parasites, Candida albicans, and possibly methicillin-resistant staphaureus.

Berberine works to:

  • Decrease insulin resistance, making the blood sugar lowering hormone more effective
  • Increase glycolysis–the breakdown of glucose inside cells
  • Decrease glucose production in the liver
  • Slow the digestion of carbohydrates
  • Increase the number of beneficial bacteria in the gut.

Berberine is a bio-active plant extract that comes from different types of plants, including goldthread, Oregon grape root, barberry, tree turmeric, and golden-seal…

It’s been used in both Ayurvedic and Chinese medicine for more than 2,500 years, and is now being used and studied extensively in the modern medical world.

Several remarkable studies show that berberine can lower blood glucose as effectively as the drug metformin, without the emasculating side-effects.

Two of the best-known peer-reviewed studies published in the Journals Metabolism and the Clinical Endocrinology, compared berberine with metformin (glucophage) in 2 separate groups…

The berberine group had very similar blood sugar lowering effects as the metformin group.

In addition, berberine also effectively reduced the patients HbA1c, triglycerides, LDL cholesterol, and blood pressure…

Three things metformin cannot do!

  • Hemoglobin A1c decreased from 9.5mg/dl to 7.5 (about 21% reduction)
  • Fasting blood glucose (FBG) decreased from 190.8 to 124.2 mg/dl
  • Postprandial blood glucose (PBG) decreased from 356.4 to 199.8 mg/dl
  • Triglycerides went down from 100.5 to 79.2 mg/dl

Berberine stimulates the absorption of glucose into the cells by improving insulin sensitivity. It also reduces glucose production in the liver.

A review published in the International Journal of Endocrinology noted: “BBR (berberine) is used to treat diabetic nephropathy (DPN), diabetic neuropathy (DN), and diabetic cardiomyopathy due to its antioxidant and anti-inflammatory properties”.

You see, berberine works by activating a metabolism-regulating enzyme within the body cells called AMPK–Adenosine Monophosphate activated Protein Kinase…

And yes…I know that’s a mouthful, but suffice it to say…

AMPK regulates a variety of biological activities that normalize lipid (fat), glucose, and energy imbalance.

Think of AMPK as your metabolic master switch…

Definitely something you want to keep flipped on.

Metabolic syndrome–a precursor to diabetes, occurs when the AMPK pathways are switched off. This triggers high blood sugar, high cholesterol, high triglycerides, and energy instability.

AMPK shifts energy to cellular repair and maintenance.

Activating AMPK produces similar benefits for diabetes and metabolic syndrome as exercise, diet and weight loss.

In a clinical study, adults took 500mg of berberine 3 times daily for 12 weeks, resulting in a drop of 5 pounds on average.

The researchers noted that, “Berberine has potential clinical application in reducing visceral fat and controlling obesity“.

Berberine has the ability to inhibit fat storage as well as improving insulin function, leptin and adiponectin.

Leptin is a very powerful hormone produced by fat cells. It tells your brain whether or not you should eat.

Leptin is the way your fat cells speak to your brain. If Leptin signaling is working optimally, it tells your brain to stop eating and storing fat once it senses a surge in body fat.

The problem is of course when the signaling goes awry, causing excessive eating and fat storage.

Adiponectin, on the other hand, is a hormone secreted by fat cells that helps control glucose regulation and fatty acid oxidation.

Obese people are often low in adiponectin, but berberine helps to increase adiponectin, which in turn helps normalize metabolic function.

The bottom line is…

Berberine could reduce the number and size of your fat cells.

Berberine is also known to enhance brown fat–a special type of heat-generating fat that burns energy instead of storing it.

It’s loaded with active mitochondria cells that convert this brown fat into energy that produces heat.

An animal study showed how berberine increases energy expenditure, helps burn fat, improves cold tolerance, and enhances active brown edipose tissue.

Berberine and Brain Health

High blood sugar levels and insulin insensitivity go hand-in-hand with memory and cognitive dysfunction.

In fact, it’s now thought that high blood sugar and diabetes are connected to an increased risk of Alzheimer’s disease.

Berberine has been found to enhance memory function in some animal studies, by preserving a brain chemical “acetylcholine“, which is important for memory, focus and cognition.

The study ultimately concluded that, berberine improved learning and memory, along with lowering oxidative stress.

Administering Berberine

According to Dr. Josh Axe, berberine should be taken 2-3 times a day.

Generally, most studies have used safe dosages starting at 500mg a dose. So, 500mg 2-3 times a day is a good starting point.

Take berberine with a meal or on a full stomach to avoid any stomach upset and to take advantage of the post meal glucose and lipid spike that often occurs.

It’s best to start with just one dose/day and increase slowly and progressively to an optimal level.

You’ll need to cut back on insulin significantly once you get started on berberine. So, monitor your blood sugar closely to avoid suffering hypoglycemia.

Many diabetics have been able to totally discontinue pharmaceutical diabetes medications, thanks to sustained use of berberine.

Look for a berberine-based product with a standardized berberine extract so that the dosages and strength are consistent.

And while at it…

Stay in consultation with your physician.

Does Berberine Have Any Side Effects?

If you have any underlying medical condition or are on any medications, including antibiotics, you’re strongly advised to consult your doctor…

This is especially important if you’re currently taking blood sugar lowering drugs, so that your physician can monitor your blood sugar and current medication levels.

Diabetics on other medications must exercise caution when using this supplement to avoid lowering blood sugar to dangerous levels.

People with low blood pressure, too, should be careful because berberine can naturally lower blood pressure.

Pregnant and breast-feeding women should not take berberine.

Overall, this natural compound has an outstanding safety profile.

Primary side-effects are minor, but could result in some cramping, diarrhea, flatulence, constipation, or mild stomach pain.

Stay on lower dosages–spread out through your day and after meals–to avoid most of the known side-effects.

In addition to its colossal benefits for diabetes, berberine loads other health benefits targeting various areas, including:

  • Anti-aging
  • Gastrointestinal infections
  • Heart disease
  • High cholesterol
  • Hypertension
  • Immune challenges
  • Joint problems
  • Low bone density

And when you’re out looking to buy berberine, don’t just buy any off the shelves…

Beware of fakes lurking in the shadows!

Instead, opt for a specific berberine-based supplement that’s clinically proven to deliver optimal blood sugar benefits.

Follow the link below to secure a top-rated option:

And by the way, have you seen this related article? Check it out–it makes a compelling read:

And needless to say, there is a lot more to learn about blood sugar…

To ensure you grab cutting-edge info and knowledge on blood sugar, I’ve meticulously pieced together a far richer resource to guarantee you picture-perfect health…

Sample it here:

Stay tuned for more…

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This article is intended to provide cutting-edge health info, and in so doing, I’ve tried to be as accurate as humanly possible. Nothing in it should be interpreted as personal medical advice. Always consult with your professional healthcare giver before changing anything related to your health.